Int J
Cancer. 2004 Jan 20;108(3):450-5. |
Les tendances d'incidence de tumeurs adultes primaires
intracérébrales dans quatre pays nordiques.
Incidence
trends of adult primary intracerebral tumors in four Nordic countries.
Lonn S, Klaeboe L, Hall P, Mathiesen T, Auvinen A, Christensen HC, Johansen
C, Salminen T, Tynes T, Feychting M.
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Stefan.Lonn@imm.ki.se
Brain tumors are some of the most lethal adult cancers and there is a concern
that the incidence is increasing. It has been suggested that the reported
increased incidence can be explained by improvements in diagnostic procedures,
although this has not been totally resolved. The aim of our study was to
describe the incidence trends of adult primary intracerebral tumors in four
Nordic countries during a period with introduction of new diagnostic procedures
and increasing prevalence of mobile phone users. Information about benign and
malignant primary intracerebral tumor cases 20-79 years of age was obtained
from the national cancer registries in Denmark, Finland, Norway and Sweden for
the years 1969-98 and estimates of person-years at risk were calculated from
the information obtained from national population registries. Annual age
standardized incidence rates per 100,000 person-years were calculated and time
trends analyses were carried out using Poisson regression. The overall
incidence of all intracerebral tumors ranged from 8.4-11.8 for men and 5.8-9.3
for women, corresponding to an average annual increase of 0.6% for men (95%
confidence interval [CI] = 0.4, 0.7) and 0.9% for women (95% CI = 0.7, 1.0).
The increase in the incidence was confined to the late 1970s and early 1980s
and coinciding with introduction of improved diagnostic methods. This increase
was largely confined to the oldest age group. After 1983 and during the period
with increasing prevalence of mobile phone users, the incidence has remained
relatively stable for both men and women. Copyright 2003 Wiley-Liss, Inc.