Am J Epidemiol 2004; 159:277-283.
Cellular Telephone Use and Risk of Acoustic Neuroma
Helle Collatz Christensen1 , Joachim Schüz2, Michael Kosteljanetz3, Hans Skovgaard Poulsen4, Jens Thomsen5 and Christoffer Johansen1
1 Institute of
Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark.
2 Institute for Medical Biostatistics, Epidemiology and Informatics, University of Mainz, Mainz, Germany.
3 Neurosurgical Department, Neuroscience Centre, University Hospital of Copenhagen, Copenhagen, Denmark.
4 Department of Radiation Biology, Finsen Centre, University Hospital of Copenhagen, Copenhagen, Denmark.
5 Department of Otolaryngology–Head and Neck Surgery, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
Despite limited evidence, cellular telephones have been claimed to cause cancer, especially in the brain. In this Danish study, the authors examined the possible association between use of cellular telephones and development of acoustic neuroma. Between 2000 and 2002, they ascertained 106 incident cases and matched these persons with 212 randomly sampled, population-based controls on age and sex. The data obtained included information on use of cellular telephones from personal interviews, data from medical records, and the results of radiologic examinations. The authors obtained information on socioeconomic factors from Statistics Denmark. The overall estimated relative risk of acoustic neuroma was 0.90 (95% confidence interval: 0.51, 1.57). Use of a cell phone for 10 years or more did not increase acoustic neuroma risk over that of short-term users. Furthermore, tumors did not occur more frequently on the side of the head on which the telephone was typically used, and the size of the tumor did not correlate with the pattern of cell phone use. The results of this prospective, population-based, nationwide study, which included a large number of long-term users of cellular telephones, do not support an association between cell phone use and risk of acoustic neuroma.